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Coffee Guards Against Deadly Prostate Cancer

Thursday, December 10, 2009 7:45 AM

By Sylvia Booth Hubbard

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Men who are java junkies could be protecting themselves against the most deadly forms of prostate cancer. A study from Harvard Medical School found that men who drank the most coffee slashed their risk of developing the fastest growing and most difficult to treat prostate cancers by more than half when compared to men who drank no coffee.

This is the first study to associate coffee with a lower risk of prostate cancer. Researchers examined the overall risk as well as the risk of localized, advanced and lethal disease. No previous studies looked at coffee and its relationship to the outcomes of various prostate cancers. "We specifically looked at different types of prostate cancer, such as advanced vs. localized cancers or high-grade vs. low-grade cancers," Kathryn M. Wilson, Ph.D., a postdoctoral fellow at Harvard Medical School, said in a statement.

Men who drank the most coffee—six or more cups daily—reduced their risk by 60 percent. The risk was 25 percent lower for men who drank four or five cups, and 20 percent lower for those men who consumed one to three cups daily.

The researchers, who studied nearly 50,000 men over a 20-year period, believe that ingredients other than caffeine provide the benefit since men who drank decaffeinated coffee enjoyed the same reduction in risk. The advantage, they theorize, probably comes from the many antioxidants and minerals found in coffee.

"This research does provide a clue that coffee drinking might reduce the likelihood of a man being diagnosed with a more advanced prostate cancer, although there is still more research to do to confirm this and to uncover which component of coffee could be responsible," Helen Rippon of the U.K.'s Prostate Cancer Charity, told the Daily Mail.

"Coffee has effects on insulin and glucose metabolism as well as sex hormone levels, all of which play a role in prostate cancer," the Harvard researchers told a conference of the American Association for Cancer Research.

"Very few lifestyle factors have been consistently associated with prostate cancer risk, especially with risk of aggressive disease, so it would be exciting if this association is confirmed in other studies."

More than 200,000 American men were diagnosed with prostate cancer this year and more than 27,000 died.

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