In Agatha Christie’s novel, Murder on the Orient Express, the killer is not one person but several, all doing their own part, acting in concert. Like most physicians, the public has been taught that diseases are most often caused by a single factor, and therefore the cure can be created by finding a single culprit. But in reality, we rarely see diseases that come from a single cause. This is especially true for neurological diseases.
It is confusing when we see reports that, for example, Alzheimer’s disease is caused by aluminum or mercury, while others insist that it is caused by repeated head injuries or exposure to pesticides. Strong evidence supports each of these causative factors.
Still other reports appear insisting that Alzheimer’s is a disease of the brain’s blood vessels or even insulin resistance in the brain.
But how could all of these things cause a single disease? The answer is that all of these “causes” trigger a common destructive mechanism that slowly destroys either the brain cells (as in Parkinson’s disease and ALS) or target their connections (dendrites and synapses) as in the case of MCI and Alzheimer’s dementia.
The common mechanism triggered by all of these events is immunoexcitotoxicity. The only medications that can slow the course of the disease are those that reduce glutamate receptor activity, or inflammation.
Find more details on how you can keep your brain from the ravages of dementia by reading my report "Save Your Brain."
A new drug combination (NitroMemantine), which suppresses excitotoxicity only, has been found to reverse the synaptic damage and symptoms in a mouse model of human Alzheimer’s disease.
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